The first reaction is impatience, but right now, he can't afford being irritated with her. The first negative reaction is coming from their first encounter, where he's like a knight of Helsing and Integra is the Queen who ordered him to search and destroy in service to her country.

"You should drink more blood. You can't afford to starve yourself. That was why you haven't been sleeping properly. It slow downs your immunity and self-healing abilities. Your abilities as a soldier were admirable, but why do you put your body under so unnecessary stress?"

With a frown, but trying to find humor, because, with all of those questions, she has proven she is clueless despite of herself. "You know, I decided to change my mind and maybe live in with you after all. If you intended to continue this working lifestyle, you'll collapse from exhaustion in the middle of the day, and I can't let that happen."

He placed a hand over her womb. "This blood bag is large because it will feed not just one, but two. Honestly, I thought most women would be perceptive of their own changes in their body and you should be smarter than me in that territory."

He cupped her chin, stroking her jawline. Showing affection isn't his strong suit, but then again when they first shared a bed, it wasn't much affectionate either, as their mating at that time is raw and primal, and through that rough mating, it was him to get her to calm down from her blood-lust and rampage from the starvation after he removed her from Brazil by force.